DEFECTIVE NEUTROPHIL MOBILITY IN TEN PATIENTS WITH VITAMIN D-DEFICIENT RICKETS
author
Abstract:
We studied the immune system, especially the chemotactic activity of neutrophils, in ten patients with vitamin D-deficient rickets and compared the results with ten healthy controls of matched age. Among all immune system factors, the chemotactic studies persistantly showed remarkable deficiency in leukocyte mobility, both random motion and migration. When compared with controls, the findings were significant. It was postulated that the increased susceptibility of the patients with vitamin D-deficient rickets to infection is mainly due to defective neutrophil Mobility
similar resources
defective neutrophil mobility in ten patients with vitamin d-deficient rickets
we studied the immune system, especially the chemotactic activity of neutrophils, in ten patients with vitamin d-deficient rickets and compared the results with ten healthy controls of matched age. among all immune system factors, the chemotactic studies persistantly showed remarkable deficiency in leukocyte mobility, both random motion and migration. when compared with controls, the findings w...
full textVitamin D–Deficient Rickets in Japan
Objectives: Our study aimed to clarify the trend of vitamin D deficiency and rickets diagnosed in the past 10 years. Methods: This observational study used health insurance claims data from 2005 to 2014. The number of beneficiaries for 2005 and 2014 were 91 617 and 365 800, respectively. We included children aged 0 to 15 years diagnosed with vitamin D deficiency or vitamin D-deficient rickets; ...
full textNEUTROPHIL CHEMOTACTIC DEFECT IN 60 PATIENTS WITH RICKETS
Neutrophil mobility in 60 patients with vitamin D-deficient rickets is studied, and the patients are followed after therapy by 600,000 units vitamin D. 28 of 60 patients (46%), had low chemotaxis for neutrophils before vitamin D injection (migration), and 36 of 60 (60%) had low random mobility. The results showed a significant improvement after vitamin D therapy furthermore, the level of c...
full textVitamin D receptor gene polymorphisms in Turkish children with vitamin D deficient rickets.
Vitamin D deficient rickets is prevalent in Turkey and a considerable number of children are at risk of growth retardation, impaired bone formation and fracture. In order to check whether vitamin D receptor (VDR) gene polymorphism relates to the vitamin D deficient rickets, we analyzed VDR gene FokI, TaqI and ApaI polymorphisms in 24 Turkish vitamin D deficient rickets patients and 100 healthy ...
full textVitamin D in health and disease: the global threat of vitamin D deficient rickets.
Nowadays, infectious diseases are less prevalent in many countries around the world and chronic diseases including obesity, diabetes, behavioral problems and nutritional deficiencies are thought to have become the major and eminent health burdens in both the adult and the young population. Among these, vitamin D deficiency poses a major health problem in children and adolescents globally. In fa...
full textAlopecia in patients with vitamin D-resistant rickets type-II*
Dear Editor, Rickets is the most common bone disease in childhood.1 The vitamin D-dependent type II (VDDR-II) is a rare and severe type of hereditary rickets described, in references worldwide, as affecting only 50 families.2 This report is designed to describe the first hereditary rickets case reported in the city of Curitiba, in which the patient displays alopecia as a frequent clinical derma...
full textMy Resources
Journal title
volume 2 issue 1
pages 29- 31
publication date 1988-05
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023